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The ACE rs1799752 Variant Is Associated with COVID-19 Severity but Is Independent of Serum ACE Activity in Hospitalized and Recovered Patients.

International journal of molecular sciences - 21 Apr 2023

Fricke-Galindo Ingrid, Buendia-Roldan Ivette, Ponce-Aguilar Daniel I, Pérez-Rubio Gloria, Chavez-Galan Leslie, Alanis-Ponce Jesús, Pérez-Torres Karina, Valencia-Pérez Rea Daniela, Téllez-Quijada Fernanda, Nava-Quiroz Karol J, Hernández-Zenteno Rafael de Jesús, Gutiérrez-Nava Angélica, Falfán-Valencia Ramcés

Abstract excerpt

This paper assesses the association of the insertion/deletion ACE (angiotensin-converting enzyme) variant (rs1799752 I/D) and the serum ACE activity with the severity of COVID-19 as well as its impact on post-COVID-19, and we compare these associations with those for patients with non-COVID-19 respiratory disorders. We studied 1252 patients with COVID-19, 104 subjects recovered from COVID-19, and 74 patients...

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Identifiers

PMID: 37108839
DOI: 10.3390/ijms24087678
PMCID: PMC10142321

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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