Article

Inhibiting CBX4 efficiently suppress YAP nucleus translocation in hepatocellular carcinoma cells to protect against sorafenib resistance

2020-05-05

Abstract excerpt

<title>Abstract</title> <p>Background The discovery of biomarkers that predict the response to sorafenib and increase the efficiency of drug therapy represents a clinical challenge. This study aimed to investigate the possible role of inhibiting CBX4 to deregulate of CSCs and to evaluate the contribution of these molecules to sorafenib resistance in advanced HCC. Methods HCC cell lines and a xenograft mouse mod...

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Literature Corpus work: 5d32f20e-ba37-582e-a252-5fe4641b2345
DOI: 10.21203/rs.3.rs-25977/v1

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