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CASK Silence Enhances Chemosensitivity of Hepatocellular Carcinoma Through activating Apoptosis, Inducing JNK/c-Jun-Mediated Autophagic Cell Death and Decreasing ABCG2

2021-01-25

Abstract excerpt

<h4>Background: </h4> Advanced hepatocellular carcinoma (HCC) patients usually fail to be treated because of drug resistance, including sorafenib. <h4>Methods: </h4>: The expression and prognostic role of calcium/calmodulin-dependent serine protein kinase (CASK) in HCC were assessed by combination of bioinformatic analysis and experimental validation. The effects of CASK in regulating proliferation, apoptosis and...

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Literature Corpus work
fbdaa584-6790-5e32-a270-4196e94ce215
DOI
10.21203/rs.3.rs-152447/v1
Open publication

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CASK Silence Enhances Chemosensitivity of Hepatocellular Carcinoma Through activating Apoptosis, Inducing JNK/c-Jun-Mediated Autophagic Cell Death and Decreasing ABCG2DOI 10.21203/rs.3.rs-152447/v1
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