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Article

Exosomal CircRNA-MANBA Mediates Hepatocellular Carcinoma Sorafenib Resistance via miR-1290/CD109/p-STAT3 Axis

2023-10-24

Abstract excerpt

<title>Abstract</title> <p>Background Sorafenib remains the cornerstone chemotherapeutic treatment for patients with late-stage hepatocellular carcinoma (HCC). Unfortunately, resistance to this drug in the context of the disease is frequent, and the underlying mechanisms remain unclear. In this regard, exosome-contained noncoding RNAs (ncRNAs) have been proven to participate in various diseases. Here, we aimed t...

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Literature Corpus work
1fcde8da-4dd2-5ccc-aa98-232b78c213ff
DOI
10.21203/rs.3.rs-3431574/v1
Open publication

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Exosomal CircRNA-MANBA Mediates Hepatocellular Carcinoma Sorafenib Resistance via miR-1290/CD109/p-STAT3 AxisDOI 10.21203/rs.3.rs-3431574/v1
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