Article

Epistatic models predict mutable sites in SARS-CoV-2 proteins and epitopes

2021-12-13

Abstract excerpt

The emergence of new variants of SARS-CoV-2 is a major concern given their potential impact on the transmissibility and pathogenicity of the virus as well as the efficacy of therapeutic interventions. Here, we predict the mutability of all positions in SARS-CoV-2 protein domains to forecast the appearance of unseen variants. Using sequence data from other coronaviruses, pre-existing to SARS-CoV-2, we build statist...

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Literature Corpus work: 5d2aaeeb-fc4a-5623-91a2-3caee9b284fa
DOI: 10.1101/2021.12.11.472202

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