Article

The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer Cells

2022-11-29

Abstract excerpt

<h4>ABSTRACT</h4> The Myc proto-oncogene contributes to the pathogenesis of more than half of human cancers. Malignant transformation by Myc transcriptionally upregulates the core pre-mRNA splicing machinery and causes mis-regulation of alternative splicing. However, our understanding of how splicing changes are directed by Myc is limited. We performed a signaling pathway-guided splicing analysis to identify Myc...

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Literature Corpus work: 5cf34929-732c-5e97-aacc-0327bb6de6c3
DOI: 10.1101/2022.11.29.518269

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The RNA binding proteins hnRNP H and F regulate splicing of a MYC dependent HRAS exon in Prostate Cancer CellsDOI 10.1101/2022.11.29.518269Read

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