Article

Loss-of-function of ALDH3B2 transdifferentiates human pancreatic duct cells into beta-like cells

2024-10-08

Abstract excerpt

<title>Abstract</title> <p>Replenishment of pancreatic beta cells is a key to the cure for diabetes. Beta cells regeneration is achieved predominantly by self-replication especially in rodents, but it was also shown that pancreatic duct cells can transdifferentiate into beta cells. How pancreatic duct cells were transdifferentiated and whether we could manipulate the transdifferentiation to replenish beta cell ma...

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Literature Corpus work: 5cdc5fbf-d1b2-5044-9a80-84dabb996c62
DOI: 10.21203/rs.3.rs-2222452/v1

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