Article

Single-cell transcriptome lineage tracing of human pancreatic development identifies distinct developmental trajectories of alpha and beta cells

2021-01-15

Abstract excerpt

<h4>ABSTRACT</h4> In comparison to mouse, the developmental process of human islets has not been properly elucidated. The advancement of single cell RNA-seq technology enables us to study the properties of alpha and beta cells at single cell resolution. By using mitochondrial genome variants as endogenous lineage-tracing markers, we found that human alpha and beta cells have different lineage features. This findi...

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Literature Corpus work: c66b7d59-3185-521b-b942-f29d7e221030
DOI: 10.1101/2021.01.14.426320

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