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Article

Causal effect of insulin resistance on small vessel stroke and Alzheimer's disease: A Mendelian randomization analysis.

European journal of neurology - 1 Mar 2022

Zhou Mengyuan, Li Hao, Wang Yongjun, Pan Yuesong, Wang Yilong

Abstract excerpt

BACKGROUND AND PURPOSE: The causal effect of insulin resistance on small vessel stroke and Alzheimer's disease (AD) was controversial in previous studies. We therefore applied Mendelian randomization (MR) analyses to identify the causal effect of insulin resistance on small vessel stroke and AD. METHODS: We selected 12 single-nucleotide polymorphisms (SNPs) associated with fasting insulin levels and five SNPs...

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PMID: 34797599
DOI: 10.1111/ene.15190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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