Article

Different transcriptome profiles between human retinoblastoma Y79 cells and an etoposide-resistant subline reveal a chemoresistance mechanism

2020-01-09

Abstract excerpt

<title>Abstract</title><p>Background: Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any differentially expressed genes (DEGs) between an etoposide drug-resistant subline (Y79/EDR) and pare...

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Literature Corpus work: 5caad585-6ac0-54f3-8423-8b328f9ef7da
DOI: 10.21203/rs.2.135/v3

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