Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Different transcriptome profiles between human retinoblastoma Y79 cells and an etoposide-resistant subline reveal a chemoresistance mechanism

6 Mar 2020

Abstract excerpt

BACKGROUND: Retinoblastoma (RB) is the most frequent pediatric retinal tumor. In the present study, to elucidate chemoresistance mechanisms and identify potential biomarkers in RB, we utilized RNA sequencing (RNAseq) technological platforms to reveal transcriptome profiles and identify any differentially expressed genes (DEGs) between an etoposide drug-resistant subline (Y79/EDR) and parental Y79 cells. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Neuroblastoma Research and Treatments
Share to Ocular Oncology and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32143590
DOI: 10.1186/s12886-020-01348-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Different transcriptome profiles between human retinoblastoma Y79 cells and an etoposide-resistant subline reveal a chemoresistance mechanismPMID 32143590Read ↗

Different transcriptome profiles between human retinoblastoma Y79 cells and an etoposide-resistant subline reveal a chemoresistance mechanismSemantic proximity Read ↗

Early Mechanisms of Chemoresistance in RetinoblastomaSemantic proximity Read ↗

RB1 loss triggers dependence on ESRRG in retinoblastomaSemantic proximity Read ↗

Protein profiling of WERI RB1 and etoposide resistant WERI ETOR reveals new insights into topoisomerase inhibitor resistance in retinoblastomaSemantic proximity Read ↗

RB1 loss triggers dependence on ESRRG in retinoblastomaSemantic proximity Read ↗

Transcriptome analysis reveals molecularly distinct subtypes in retinoblastomaSemantic proximity Read ↗

Retinoblastoma: A review of the molecular basis of tumor development and its clinical correlation in shaping future targeted treatment strategiesSemantic proximity Read ↗

Functional genomics identifies new synergistic therapies for retinoblastomaSemantic proximity Read ↗

Genetic and Epigenetic Discoveries in Human RetinoblastomaSemantic proximity Read ↗

A high-risk retinoblastoma subtype with stemness features, dedifferentiated cone states and neuronal/ganglion cell gene expression.Semantic proximity Read ↗

Single-cell characterization of malignant phenotypes and microenvironment alteration in retinoblastoma.Semantic proximity Read ↗

Retinoblastoma: emerging concepts in genetics, global disease burden, chemotherapy outcomes, and psychological impactSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.