Article

Harvesting and amplifying gene cassettes confers cross-resistance to critically important antibiotics

2023-12-04

Abstract excerpt

Amikacin and piperacillin/tazobactam are frequent antibiotic choices to treat bloodstream infection, which is commonly fatal and most often caused by bacteria from the family Enterobacterales . Here we show that two gene cassettes located side-by-side in and ancestral integron similar to In 37 have been “harvested” by insertion sequence IS 26 as a transposon that is already globally disseminated among the Ente...

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Literature Corpus work: 5c6a7660-5dbc-5ad5-9c35-57f49c53b5aa
DOI: 10.1101/2023.12.02.569715

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