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Metagenomic and whole-genome characterization of carbapenem-resistant Acinetobacter baumannii carrying blaOXA-23 gene within the Tn2006 transposon among ICU patients.

Journal of global antimicrobial resistance - 1 Sept 2025

Ying Senhong, Zhang Zhirong, Xiang Rong

Abstract excerpt

PURPOSE: To characterize carbapenem-resistant Acinetobacter baumannii carrying blaOXA-23 genes within the Tn2006 transposon using metagenomic and whole-genome sequencing, focusing on their genetic features, antimicrobial resistance, and potential for clonal spread and horizontal gene transfer among intensive care unit (ICU) patients. METHODS: Bronchoalveolar lavage fluid samples from 28 ICU patients were analysed...

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PMID: 40555322
DOI: 10.1016/j.jgar.2025.06.009

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