Article

Synaptophysin is a β-Amyloid Target that Regulates Synaptic Plasticity and Seizure Susceptibility in an Alzhiemer’s Model

2017-04-24

Abstract excerpt

<h4>Intro/abstract</h4> Alzheimer’s disease (AD), a condition characterized by cognitive deficits and progressive loss of memory, is causally linked to the short amyloid peptide Aβ42, which disrupts normal neurotransmission 1,2 . Neurotransmitter (NT) release from synaptic vesicles (SV) requires coordinated binding of the conserved core secretory machinery comprised of the soluble NSF attachment protein receptor...

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Literature Corpus work: 5c5f82eb-5326-544a-9a21-ac74b4eacf21
DOI: 10.1101/129551

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