Article

Low expression of Isocitrate Dehydrogenase 1 (IDH1) R132H is associated with advanced pathological features in laryngeal squamous cell carcinoma

2022-07-28

Abstract excerpt

<h4>Introduction: </h4> Recent developments in genomic sequencing have led to the identification of somatic mutations in isocitrate dehydrogenase 1 (IDH1) in various malignancies. IDH1 R132H is the most common mutation of IDH1, which affects codon 132 and results in the conversion of amino acid residue arginine (R) to histidine (H). The expression and clinical significance of IDH1 R132H in laryngeal squamous cell...

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Literature Corpus work: 5c1f16dd-8198-5706-ad3d-a8f4b522269b
DOI: 10.21203/rs.3.rs-1885687/v1

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