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Article

Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer.

Oncotarget - 8 Nov 2016

Li Jieying, Huang Jianfei, Huang Fang, Jin Qing, Zhu Huijun, Wang Xudong, Chen Meng

Abstract excerpt

Isocitrate dehydrogenase (IDH1) is an NADP-dependent enzyme that catalyzes the decarboxylation of isocitrate to alpha-ketoglutarate. The IDH1-R132H mutation predicts a better clinical outcome for glioma patients, and the expression of IDH1-R132H correlates with a favorable outcome in patients with brain tumors. Here, we investigated IDH1-R132H expression in both gastric (n=526) and colorectal (n=399) tissues by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27655638
DOI: 10.18632/oncotarget.12039
PMCID: PMC5342004

Genes

IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer.PMID 27655638Read ↗

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