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Article

Antibody Structure and Function: The Basis for Engineering Therapeutics

3 Dec 2019

Abstract excerpt

Antibodies and antibody-derived macromolecules have established themselves as the mainstay in protein-based therapeutic molecules (biologics). Our knowledge of the structure-function relationships of antibodies provides a platform for protein engineering that has been exploited to generate a wide range of biologics for a host of therapeutic indications. In this review, our basic understanding of the antibody...

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Identifiers

PMID: 31816964
DOI: 10.3390/antib8040055

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