Article

Evidence for a relationship between genetic polymorphisms of the L-DOPA transporter LAT2/4F2hc and risk of hypertension in the context of chronic kidney disease

2024-04-03

Abstract excerpt

<title>Abstract</title> <p>Background Chronic kidney disease (CKD) and hypertension are chronic diseases affecting a large portion of the population, frequently coexistent and interdependent. The inability to produce/use adequate renal dopamine may contribute to the development of hypertension and renal dysfunction. The heterodimeric amino acid transporter LAT2/4F2hc (<italic>SLC7A8/SLC3A2</italic> genes) promot...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5bb60614-4d61-508c-a0cc-cfd5e202e667
DOI: 10.21203/rs.3.rs-4162158/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evidence for a relationship between genetic polymorphisms of the L-DOPA transporter LAT2/4F2hc and risk of hypertension in the context of chronic kidney diseaseDOI 10.21203/rs.3.rs-4162158/v1Read

Evidence for a relationship between genetic polymorphisms of the L-DOPA transporter LAT2/4F2hc and risk of hypertension in the context of chronic kidney disease.Semantic proximity Read

Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.Semantic proximity Read

Association of the SLC22A1, SLC22A2, and SLC22A3 genes encoding organic cation transporters with diabetic nephropathy and hypertension.Semantic proximity Read

Evaluation of neurotrophic tyrosine receptor kinase 2 (NTRK2) as a positional candidate gene for variation in estimated glomerular filtration rate (eGFR) in Mexican American participants of San Antonio Family Heart study.Semantic proximity Read

Impact of solute carrier transporter gene polymorphisms on serum creatinine concentrations in healthy volunteers.Semantic proximity Read

Association between SLC20A1 and sodium-lithium countertransport.Semantic proximity Read

Association between NEDD4L gene and sodium lithium countertransport.Semantic proximity Read

Physical decline and survival in the elderly are affected by the genetic variability of amino acid transporter genes.Semantic proximity Read

Lower prevalence of the OCT2 Ser270 allele in patients with essential hypertension.Semantic proximity Read

Genetic and Functional Study of L-Type Amino Acid Transporter 1 in Schizophrenia.Semantic proximity Read

Genetic variants in renalase and blood pressure responses to dietary salt and potassium interventions: a family-based association study.Semantic proximity Read

A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism.Semantic proximity Read