Article
Association between SLC20A1 and sodium-lithium countertransport.
American journal of hypertension - 1 Oct 2011
Zheng Xiaojing, Morrison Alanna C, Turner Stephen T, Ferrell Robert E
Abstract excerpt
BACKGROUND: Sodium-lithium countertransport (SLC) is a premorbidity marker of essential hypertension. Evidence from linkage analysis and kinetic studies in humans have suggested that SLC20A1 variations may affect SLC activity as measured in erythrocytes and leukocytes. SLC20A1 encodes a sodium-dependent phosphate cotransporter, and is widely expressed on the mammalian plasma membrane. In this study, we...
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