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Article

Physical decline and survival in the elderly are affected by the genetic variability of amino acid transporter genes.

Aging - 18 Apr 2018

Crocco Paolina, Hoxha Eneida, Dato Serena, De Rango Francesco, Montesanto Alberto, Rose Giuseppina, Passarino Giuseppe

Abstract excerpt

Amino acid (AA) availability is a rate-limiting factor in the regulation of muscle protein metabolism and, consequently, a risk factor for age-related decline in muscle performance. AA transporters are emerging as sensors of AA availability and activators of mTORC1 signalling, acting as transceptors. Here, we evaluated the association of 58 single nucleotide polymorphisms (SNPs) in 10 selected AA transporter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29676995
DOI: 10.18632/aging.101420
PMCID: PMC5940118

Genes

LAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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