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Achieving Resilience in Aging: How Mitochondrial Modulation Drives Age-associated Fluconazole Tolerance in <i>Cryptococcus neoformans</i>

2024-03-26

Abstract excerpt

<h4>ABSTRACT</h4> Cryptococcus neoformans ( Cn ) is an opportunistic fungal microorganism that causes life-threatening meningoencephalitis. During the infection, the microbial population is heterogeneously composed of cells with varying generational ages, with older cells accumulating during chronic infections. This is attributed to their enhanced resistance to phagocytic killing and tolerance of antifungals lik...

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Literature Corpus work: 5b805cdb-29de-56d9-a580-7d0925985187
DOI: 10.1101/2024.03.26.586817

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