Article

Metabolic plasticity and virulence of <i>Cryptococcus neoformans</i> are regulated by mitochondrial homeostasis

2026-02-10

Abstract excerpt

The mitochondrion is a versatile organelle involved in diverse processes, such as cell death, metal homeostasis, plasma membrane and cell wall integrity, stress response, oxygen concentration, temperature, and metabolic adaptation, in addition to its role in generating energy. Consequently, mitochondrial fitness is essential for the pathogenicity of various organisms, including fungi. Cryptococcus neoformans is a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c6c1c763-e31c-5172-aff9-2796ae3112ec
DOI: 10.64898/2026.02.06.704083

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Metabolic plasticity and virulence of <i>Cryptococcus neoformans</i> are regulated by mitochondrial homeostasisDOI 10.64898/2026.02.06.704083Read

Respiring to infect: Emerging links between mitochondria, the electron transport chain, and fungal pathogenesisSemantic proximity Read

Metabolic control of mitochondrial plasticity and extracellular vesicle biology drives Cryptococcus neoformans virulenceSemantic proximity Read

Uncovering the role of mitochondrial genome in pathogenicity and drug resistance in pathogenic fungiSemantic proximity Read

<i>Cryptococcus neoformans</i> resist to drastic conditions by switching to viable but non-culturable cell phenotypeSemantic proximity Read

The interplay between electron transport chain function and iron regulatory factors influences melanin formation in <i>Cryptococcus neoformans</i>Semantic proximity Read

Maintenance of Mitochondrial Morphology in Cryptococcus neoformans Is Critical for Stress Resistance and VirulenceSemantic proximity Read

Role of Amino Acid Metabolism in the Virulence of Human Pathogenic FungiSemantic proximity Read

<i>Cryptococcus neoformans</i> adapts to host CO <sub>2</sub> concentrations through the coordinated remodeling of central carbon metabolism, oxidative stress resistance, and membrane homeostasisSemantic proximity Read

Cryptococcus neoformans resists to drastic conditions by switching to viable but non-culturable cell phenotype.Semantic proximity Read

The fungal pathogen Cryptococcus neoformans adapts to the host environment through TOR-mediated remodeling of phospholipid asymmetrySemantic proximity Read

Achieving Resilience in Aging: How Mitochondrial Modulation Drives Age-associated Fluconazole Tolerance in <i>Cryptococcus neoformans</i>Semantic proximity Read

Peroxisomes regulate virulence and cell density sensing in <i>Cryptococcus neoformans</i>Semantic proximity Read