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Replicative Aging in Pathogenic Fungi

25 Dec 2020

Abstract excerpt

Candida albicans, Candida auris, Candida glabrata, and Cryptococcus neoformans are pathogenic yeasts which can cause systemic infections in immune-compromised as well as immune-competent individuals. These yeasts undergo replicative aging analogous to a process first described in the nonpathogenic yeast Saccharomyces cerevisiae. The hallmark of replicative aging is the asymmetric cell division of mother yeast...

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PMID: 33375605
DOI: 10.3390/jof7010006

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