Article

<i>Cryptococcus neoformans</i> resist to drastic conditions by switching to viable but non-culturable cell phenotype

2019-02-18

Abstract excerpt

Metabolically quiescent pathogens can persist in a viable non-replicating state for months or even years. For certain infectious diseases, such as tuberculosis, cryptococcosis, histoplasmosis, latent infection is a corollary of this dormant state, which has the risk for reactivation and clinical disease. During murine cryptococcosis and macrophage uptake, stress and host immunity induce C. neoformans heterogeneity...

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Literature Corpus work: 3ee83e37-dee5-5447-8539-5d067891dc48
DOI: 10.1101/552836

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