Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host.

PLoS pathogens - 1 May 2017

Bouklas Tejas, Alonso-Crisóstomo Luz, Székely Tamás, Diago-Navarro Elizabeth, Orner Erika P, Smith Kalie, Munshi Mansa A, Del Poeta Maurizio, Balázsi Gábor, Fries Bettina C

Abstract excerpt

Similar to other yeasts, the human pathogen Candida glabrata ages when it undergoes asymmetric, finite cell divisions, which determines its replicative lifespan. We sought to investigate if and how aging changes resilience of C. glabrata populations in the host environment. Our data demonstrate that old C. glabrata are more resistant to hydrogen peroxide and neutrophil killing, whereas young cells adhere better...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Candida glabrata

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Candidiasis

Share to Drug Resistance, Fungal

Share to Fluconazole

Share to Hydrogen Peroxide

Share to Neutrophils

Source

Open in PubMed Open full text

Identifiers

PMID: 28489916
DOI: 10.1371/journal.ppat.1006355
PMCID: PMC5440053

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generational distribution of a Candida glabrata population: Resilient old cells prevail, while younger cells dominate in the vulnerable host.PMID 28489916Read ↗

Replicative Aging Remodels Cell Wall and is Associated with Increased Intracellular Trafficking in Human Pathogenic YeastsSemantic proximity Read ↗

Replicative Aging Remodels the Cell Wall and Is Associated with Increased Intracellular Trafficking in Human Pathogenic YeastsSemantic proximity Read ↗

Aging as an emergent factor that contributes to phenotypic variation in Cryptococcus neoformans.Semantic proximity Read ↗

Old Cryptococcus neoformans Cells Contribute to Virulence in Chronic CryptococcosisSemantic proximity Read ↗

Achieving Resilience in Aging: How Mitochondrial Modulation Drives Age-associated Fluconazole Tolerance in <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Replicative Aging in Pathogenic FungiSemantic proximity Read ↗

High-Throughput Yeast Aging Analysis for Cryptococcus (HYAAC) microfluidic device streamlines aging studies in Cryptococcus neoformans.Semantic proximity Read ↗

Aging: an emergent phenotypic trait that contributes to the virulence of Cryptococcus neoformans.Semantic proximity Read ↗

Cell Wall-Associated Virulence Factors Contribute to Increased Resilience of Old Cryptococcus neoformans CellsSemantic proximity Read ↗

Cryptococcus neoformans Host Adaptation: Toward Biological Evidence of DormancySemantic proximity Read ↗

Isolation and characterization of senescent Cryptococcus neoformans and implications for phenotypic switching and pathogenesis in chronic cryptococcosis.Semantic proximity Read ↗

Global analysis of fungal morphology exposes mechanisms of host cell escapeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.