Article

Multiparameter cell characterization using nanofluidic technology facilitates real-time phenotypic and genotypic elucidation of intratumor heterogeneity

2018-10-31

Abstract excerpt

<h4>ABSTRACT</h4> Genetic and functional complexity of bulk tumor has become evident through rapid advances in sequencing technologies. As a unique integrated approach to characterizing tumor heterogeneity, we demonstrate the multifaceted capabilities of a novel nanofluidic platform to enable single-cell phenotypic and genetic profiling of ovarian cancer patient-derived tumor cells. This approach has enabled incr...

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Literature Corpus work: 5b77c454-adcc-5685-8be9-479b94afe657
DOI: 10.1101/457010

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