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Single‐cell profiling approaches to probing tumor heterogeneity

20 Jan 2016

Abstract excerpt

Tumor heterogeneity is a major hindrance in cancer classification, diagnosis and treatment. Recent technological advances have begun to reveal the true extent of its heterogeneity. Single-cell analysis (SCA) is emerging as an important approach to detect variations in morphology, genetic or proteomic expression. In this review, we revisit the issue of inter- and intra-tumor heterogeneity, and list various modes...

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PMID: 26789729
DOI: 10.1002/ijc.30006

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