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Article

Single-cell sequencing in ovarian cancer: a new frontier in precision medicine

30 Nov 2018

Abstract excerpt

PURPOSE OF REVIEW: This article discusses the advances, applications and challenges of using single-cell RNA sequencing data in guiding treatment decisions for ovarian cancer. RECENT FINDINGS: Genetic heterogeneity is a hallmark of ovarian cancer biology and underlies treatment resistance. Defining the different cell types present within a single ovarian cancer is difficult, but could ultimately lead to...

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PMID: 30507625
DOI: 10.1097/gco.0000000000000516

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