Article

Substance P/neurokinin1 receptor is associated with the expression of cardiac stem/pluripotency-associated genes in diabetic right and left atria

2021-03-01

Abstract excerpt

Substance P (SP) is a cardioprotective neuropeptide that interacts with the G protein-coupled neurokinin-1 receptor (NK1R). Although the expression of SP/NK1R in the right atrium (RA) of diabetic patients is known to be significantly impaired, the molecular mechanism remains unclear. LETO and OLETF rats were randomly divided into 3 groups: saline, SP injection (5 nmole/kg), and SP+RP injection (1 mg/kg RP67580, a...

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Literature Corpus work: 5b71bf6f-ce86-522b-9a0f-201267d65e0a
DOI: 10.21203/rs.3.rs-254561/v1

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