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Screening and Identification of Key Genes for Activation of Islet Stellate Cell

9 Sept 2021

Abstract excerpt

Background It has been demonstrated that activated islet stellate cells (ISCs) play a critical role in islet fibrogenesis and significantly contribute to the progression of type 2 diabetes mellitus. However, the key molecules responsible for ISCs activation have not yet been determined. This study aimed to identify the potential key genes involved in diabetes-induced activation of ISCs. Method Stellate cells were...

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PMID: 34566887
DOI: 10.3389/fendo.2021.695467

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