Article
Neuropeptide SP activates the WNT signal transduction pathway and enhances the proliferation of bone marrow stromal stem cells.
Cell biology international - 1 Nov 2013
Mei Gang, Xia Liheng, Zhou Jian, Zhang Yongtao, Tuo Yonghua, Fu Su, Zou Zhenlv, Wang Zhao, Jin Dan
Abstract excerpt
Substance P (SP) mediates multiple activities in various cell types, such as proliferation, anti-apoptotic response, and inflammation. We have investigated the effects of SP, NK1 antagonist and DKK1 on proliferation of bone marrow stromal stem cells (BMSCs), as well as the underlying mechanism. I...
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