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A Prokineticin-Driven Epigenetic Switch Regulates Human Epicardial Cell Stemness and Fate

6 Jun 2018

Abstract excerpt

Epicardial adipose tissues (EATs) and vascular tissues may both belong to the mesoepithelial lineage that develops from epicardium-derived progenitor cells (EPDCs) in developing and injured hearts. Very little is known of the molecular mechanisms of EPDC contribution in EAT development and neovascularization in adult heart, which the topic remains a subject of intense therapeutic interest and scientific debate....

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PMID: 29873146
DOI: 10.1002/stem.2866

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