Article

Enhancer-driven gene regulatory networks inference from single-cell RNA-seq and ATAC-seq data

2022-12-15

Abstract excerpt

<h4>ABSTRACT</h4> Deciphering the intricate relationships between transcription factors (TFs), enhancers, and genes through the inference of enhancer-driven gene regulatory networks is crucial in understanding gene regulatory programs in a complex biological system. This study introduces STREAM, a novel method that leverages a Steiner Forest Problem model, a hybrid biclustering pipeline, and submodular optimizati...

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Literature Corpus work: 5b61d3da-47e6-54cd-9331-49b7b66d03b0
DOI: 10.1101/2022.12.15.520582

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