Article

RNA-Seq in 296 phased trios provides a high resolution map of genomic imprinting

2018-02-21

Abstract excerpt

Combining allelic analysis of RNA-Seq data with phased genotypes in family trios provides a powerful method to detect parent-of-origin biases in gene expression. We report findings in 296 family trios from two large studies: 165 lymphoblastoid cell lines from the 1000 Genomes Project, and 131 blood samples from the Genome of the Netherlands participants (GoNL). Based on parental haplotypes we identified >2.8 milli...

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Literature Corpus work: 5b3fb3ef-adfd-5668-be2e-e8e5d388bb3a
DOI: 10.1101/269449

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