Article
A genome-wide approach to identifying novel-imprinted genes.
Human genetics - 1 Jan 2008
Pollard Katherine S, Serre David, Wang Xu, Tao Heng, Grundberg Elin, Hudson Thomas J, Clark Andrew G, Frazer Kelly
Abstract excerpt
Genomic imprinting is an epigenetic process in which the copy of a gene inherited from one parent (maternal or paternal) is consistently silenced or expressed at a significantly lower level than the copy from the other parent. In an effort to begin a systematic genome-wide screen for imprinted genes, we assayed differential allelic expression (DAE) at 3,877 bi-allelic protein-coding sites located in 2,625 human...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
