Article
Parent of origin gene expression in a founder population identifies two new candidate imprinted genes at known imprinted regions.
PloS one - 1 Jan 2018
Mozaffari Sahar V, Stein Michelle M, Magnaye Kevin M, Nicolae Dan L, Ober Carole
Abstract excerpt
Genomic imprinting is the phenomena that leads to silencing of one copy of a gene inherited from a specific parent. Mutations in imprinted regions have been involved in diseases showing parent of origin effects. Identifying genes with evidence of parent of origin expression patterns in family studies allows the detection of more subtle imprinting. Here, we use allele specific expression in lymphoblastoid cell...
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