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Article

Detection of Imprinted Genes by Single-Cell Allele-Specific Gene Expression.

American journal of human genetics - 2 Mar 2017

Santoni Federico A, Stamoulis Georgios, Garieri Marco, Falconnet Emilie, Ribaux Pascale, Borel Christelle, Antonarakis Stylianos E

Abstract excerpt

Genomic imprinting results in parental-specific gene expression. Imprinted genes are involved in the etiology of rare syndromes and have been associated with common diseases such as diabetes and cancer. Standard RNA bulk cell sequencing applied to whole-tissue samples has been used to detect imprinted genes in human and mouse models. However, lowly expressed genes cannot be detected by using RNA bulk approaches....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28190458
DOI: 10.1016/j.ajhg.2017.01.028
PMCID: PMC5339288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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