Article

New lessons on TDP-43 from the killifish <i>N. furzeri</i>

2021-02-05

Abstract excerpt

Frontotemporal dementia and amyotrophic lateral sclerosis are fatal and incurable neurodegenerative diseases linked to the pathological aggregation of the TDP-43 protein. This is an essential DNA/RNA binding protein involved in transcription regulation, pre-RNA processing and RNA transport. Having suitable animal models to study the mechanisms of TDP-43 aggregation is crucial to develop treatments against disease....

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Literature Corpus work: 5ae8ca28-4637-5e22-a5c2-6ffafebc59c1
DOI: 10.1101/2021.02.04.429704

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