Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New lessons on TDP‐43 from old N. furzeri killifish

23 Dec 2021

Abstract excerpt

Frontotemporal dementia and amyotrophic lateral sclerosis are fatal and incurable neurodegenerative diseases linked to the pathological aggregation of the TDP-43 protein. This is an essential DNA/RNA-binding protein involved in transcription regulation, pre-RNA processing, and RNA transport. Having suitable animal models to study the mechanisms of TDP-43 aggregation is crucial to develop treatments against...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Amyotrophic Lateral Sclerosis Research
Share to Neuroinflammation and Neurodegeneration Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34939315
DOI: 10.1111/acel.13517

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New lessons on TDP‐43 from old N. furzeri killifishPMID 34939315Read ↗

New lessons on TDP-43 from the killifish <i>N. furzeri</i>Semantic proximity Read ↗

Functional Significance of TDP-43 Mutations in Disease.Semantic proximity Read ↗

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicitySemantic proximity Read ↗

Disease causing mutants of TDP-43 nucleic acid binding domains are resistant to aggregation and have increased stability and half-life.Semantic proximity Read ↗

Mechanisms of TDP-43 Proteinopathy Onset and Propagation.Semantic proximity Read ↗

TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathiesSemantic proximity Read ↗

Molecular Dissection of TDP-43 ProteinopathiesSemantic proximity Read ↗

TDP-43: a novel neurodegenerative proteinopathySemantic proximity Read ↗

Biology and Pathobiology of TDP-43 and Emergent Therapeutic Strategies.Semantic proximity Read ↗

The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtinSemantic proximity Read ↗

Identification of protein aggregates in the aging vertebrate brain with prion-like and phase separation propertiesSemantic proximity Read ↗

RNA-binding proteins with prion-like domains in ALS and FTLD-USemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.