Article

Asparagine endopeptidase promotes radioresistance in breast cancer through ATR pathway modulation

2025-01-15

Abstract excerpt

<h4>Background</h4> Tumor resistance represents a major challenge in the current oncology landscape. Asparagine endopeptidase (AEP) overexpression correlates with worse prognosis and reduced overall survival in most human solid tumors. However, the underlying mechanisms of the connection between AEP and reduced overall survival in cancer patients remain unclear. <h4>Methods</h4> High-throughput proteomics, cellu...

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Literature Corpus work: 5adf51c1-dfd3-5de9-ad13-04054ff54b26
DOI: 10.1101/2025.01.13.632704

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