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Article

Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2018

Schmitz Corinna, Noels Heidi, El Bounkari Omar, Straussfeld Eva, Megens Remco T A, Sternkopf Marieke, Alampour-Rajabi Setareh, Krammer Christine, Tilstam Pathricia V, Gerdes Norbert, Bürger Christina, Kapurniotu Aphrodite, Bucala Richard, Jankowski Joachim, Weber Christian, Bernhagen Jürgen

Abstract excerpt

The inflammatory cytokine macrophage migration-inhibitory factor (MIF) promotes atherosclerosis via lesional monocyte and T-cell recruitment. B cells have emerged as important components in atherogenesis, but the interaction between MIF and B cells in atherogenesis is unknown. Here, we investigated the atherosclerotic phenotype of Mif-gene deletion in Apoe-/- mice. Apoe-/- Mif-/- mice fed a Western diet exhibited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29543531
DOI: 10.1096/fj.201800058R
PMCID: PMC6207164

Genes

MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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