Article

Computational mutagenesis by using AUTO-MUTE 2.0 to examine X-ray crystallography structures for p53 and the impact of its resolution on predictions

2023-01-04

Abstract excerpt

<h4>ABSTRACT</h4> The mutation of P53 is found in 50% of all human cancers, affecting the protein structure conformation, which further impacts its function. Identifying the appropriate protein structure for future research has been challenging. Many X-ray crystallography structures exist in the Protein Data Bank (PDB) for a given protein. We compared two proteins with different resolutions to determine whether t...

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Literature Corpus work: 5a5d8d88-a91b-560c-ad59-7c849971bdda
DOI: 10.1101/2023.01.03.522606

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Computational mutagenesis by using AUTO-MUTE 2.0 to examine X-ray crystallography structures for p53 and the impact of its resolution on predictionsDOI 10.1101/2023.01.03.522606Read

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