Article

Sleep-wake Characteristics in a Mouse Model of Severe Traumatic Brain Injury: Relation to Post-Traumatic Epilepsy

2020-06-16

Abstract excerpt

<h4>Study objectives</h4> Traumatic brain injury (TBI) results in sequelae that include post-traumatic epilepsy (PTE) and sleep-wake disturbances. Here we sought to determine whether sleep characteristics could predict development of PTE in a model of severe TBI. <h4>Methods</h4> Following controlled cortical impact (CCI), sham injury (craniotomy only) or no craniotomy (NC), CD-1 mice were implanted with epidura...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5a56734c-44d4-5e58-9439-8a317aa85386
DOI: 10.1101/2020.06.16.137034

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sleep-wake Characteristics in a Mouse Model of Severe Traumatic Brain Injury: Relation to Post-Traumatic EpilepsyDOI 10.1101/2020.06.16.137034Read

Sleep Disruption in a Mouse Model of Chronic Traumatic Brain InjurySemantic proximity Read

Persistent Hypersomnia Following Repetitive Mild Experimental Traumatic Brain Injury: Roles of Chronic Stress and Sex DifferencesSemantic proximity Read

Sleep-Wake Disturbances After Traumatic Brain Injury: Synthesis of Human and Animal Studies.Semantic proximity Read

A novel mouse model of focal limbic seizures that reproduces behavioral impairment associated with cortical slow wave activitySemantic proximity Read

Epilepsy phenotype and its reproducibility after lateral fluid percussion-induced traumatic brain injury in rats: Multicenter EpiBioS4Rx study project 1.Semantic proximity Read

Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury.Semantic proximity Read

Genetic diversity drives extreme responses to traumatic brain injury and post-traumatic epilepsy.Semantic proximity Read

Photothrombosis induced cortical stroke produces electrographic epileptic biomarkers in miceSemantic proximity Read

Home-cage Monitoring Ascertains Signatures of Ictal and Interictal Behavior In Mouse Models of Generalized SeizuresSemantic proximity Read

Individualized and stereotypical seizure semiology in a porcine model of post-traumatic epilepsySemantic proximity Read

Elevation of MMP-9 Levels Promotes Epileptogenesis After Traumatic Brain Injury.Semantic proximity Read

Cortico-autonomic local arousals and heightened somatosensory arousability during NREM sleep of mice in neuropathic painSemantic proximity Read