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Article

Genetic diversity drives extreme responses to traumatic brain injury and post-traumatic epilepsy.

Experimental neurology - 1 Apr 2024

Shannon Tyler, Cotter Christopher, Fitzgerald Julie, Houle Samuel, Levine Noah, Shen Yuyan, Rajjoub Noora, Dobres Shannon, Iyer Sidharth, Xenakis James, Lynch Rachel, de Villena Fernando Pardo-Manuel, Kokiko-Cochran Olga, Gu Bin

Abstract excerpt

Traumatic brain injury (TBI) is a complex and heterogeneous condition that can cause wide-spectral neurological sequelae such as behavioral deficits, sleep abnormalities, and post-traumatic epilepsy (PTE). However, understanding the interaction of TBI phenome is challenging because few animal models can recapitulate the heterogeneity of TBI outcomes. We leveraged the genetically diverse recombinant inbred...

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PMID: 38185315
DOI: 10.1016/j.expneurol.2024.114677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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