Back to search

Article

Photothrombosis induced cortical stroke produces electrographic epileptic biomarkers in mice

2024-03-04

Abstract excerpt

<h4>Objective</h4> Interictal epileptiform spikes, high-frequency ripple oscillations, and their co-occurrence (spike ripples) in human scalp or intracranial voltage recordings are well-established epileptic biomarkers. While clinically significant, the neural mechanisms generating these electrographic biomarkers remain unclear. To reduce this knowledge gap, we introduce a novel photothrombotic stroke model in mi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
99ee4f79-1b93-5a16-ad4c-45b231036a94
DOI
10.1101/2024.03.01.582958
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Photothrombosis induced cortical stroke produces electrographic epileptic biomarkers in miceDOI 10.1101/2024.03.01.582958
Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humansSemantic proximity
Photothrombotic Ischemic Thalamic Stroke in Mice Recapitulates Spontaneous Pain Features of Central Post-Stroke Pain in HumansSemantic proximity
High Frequency Oscillations (>250Hz) Outnumber Interictal Spikes in Preclinical Studies of Alzheimer’s DiseaseSemantic proximity
An automated, machine learning-based detection algorithm for spike-wave discharges (SWDs) in a mouse model of absence epilepsySemantic proximity
High-frequency oscillations arise through distinct mechanisms in models of α- synucleinopathy and channelopathy-induced epilepsySemantic proximity
Involvement of remote regions in sustained, but not transient, epileptic activities in the kainate mouse model of temporal lobe epilepsySemantic proximity
Region-specific spreading depolarization drives aberrant post-ictal behaviorSemantic proximity
A novel mouse model of focal limbic seizures that reproduces behavioral impairment associated with cortical slow wave activitySemantic proximity
A python-based package for long-lasting video acquisition and semi-automated detection of convulsive seizures in rodentsSemantic proximity
Waveform-based classification of dentate spikesSemantic proximity
Electrographic significance of Periodic Discharges and association with etiology and outcome in tertiary care hospital, a retrospective cohort studySemantic proximity
Cortical Spreading Depression Can Be Triggered by Sensory Stimulation in Primed Wild Type Mouse Brain: a Mechanistic Insight to Migraine Aura GenerationSemantic proximity
Select a neighboring publication to make it the new centre.