Article
Chronic outcomes after mild-moderate traumatic brain injury in adult seizure-prone (FAST) and seizure-resistant (SLOW) rats: A model for understanding genetic contributions to acquired epileptogenesis?
Epilepsy & behavior : E&B - 1 May 2025
Leung Wai Lam, Shad Ali, Perucca Piero, O'Brien Terence J, Semple Bridgette D, Casillas-Espinosa Pablo M
Abstract excerpt
Post-traumatic epilepsy (PTE) is a common, serious, long-term complication of traumatic brain injury (TBI). However, only a minority of individuals will develop epilepsy after a TBI, and the contribution of genetic predisposition to the risk of acquired epilepsy warrants further exploration. In this study, we examined whether innate, genetically determined differences in seizure susceptibility between...
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- Animals
- Rats
- Disease Models, Animal
- Male
- Epilepsy, Post-Traumatic
- Seizures