Article

Characterization of an <i>Osmr</i> Conditional Knockout Mouse Model

2023-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Oncostatin M (OSM) is a member of the interleukin-6 (IL-6) family of cytokines and has been found to have distinct anti-inflammatory and pro-inflammatory properties in various cellular and disease contexts. OSM signals through two receptor complexes, one of which includes OSMRβ. To investigate OSM-OSMRβ signaling in adult hematopoiesis, we utilized the readily available conditional Osmr fl/fl m...

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Literature Corpus work: 5a19c8da-71fd-5ded-8ee7-c56f6db29c72
DOI: 10.1101/2023.10.27.564474

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