Article

Protein kinase C eta enhances Golgi-localized signaling and is associated with Alzheimer’s disease using a recessive mode of inheritance

2025-05-14

Abstract excerpt

The identification of Alzheimer’s disease (AD)-associated genomic variants has provided powerful insight into disease etiology. Genome-wide association studies (GWAS) for AD have successfully identified new targets but have almost exclusively utilized additive genetic models. Here, we performed a family-based GWAS under a recessive inheritance model using whole genome sequencing from families affected by AD. We fo...

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Literature Corpus work: 59ef33ea-6cd0-5a5d-8f43-c40bbb90c706
DOI: 10.1101/2025.05.13.25327562

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