Article
Estimating meiotic gene conversion rates from population genetic data.
Genetics - 1 Oct 2007
Gay J, Myers S, McVean G
Abstract excerpt
Gene conversion plays an important part in shaping genetic diversity in populations, yet estimating the rate at which it occurs is difficult because of the short lengths of DNA involved. We have developed a new statistical approach to estimating gene conversion rates from genetic variation, by extending an existing model for haplotype data in the presence of crossover events. We show, by simulation, that when the...
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