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Article

Impact of Serum Circulating Factors and PDE5 Inhibitor Therapy on Cardiomyocyte Metabolism in Single Ventricle Heart Disease

2025-04-01

Abstract excerpt

<h4>Background</h4> While operative and perioperative care continues to improve for single ventricle congenital heart disease (SV), long-term morbidities and mortality remain high. Importantly, phosphodiesterase-5 inhibitor therapies (PDE5i) are increasingly used, however, little is known regarding the direct myocardial effects of PDE5i therapy in the SV population. <h4>Objectives</h4> Our group has previously d...

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Literature Corpus work
59b441e4-5568-53ee-8970-2d883ea04868
DOI
10.1101/2025.03.31.646497
Open publication

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Impact of Serum Circulating Factors and PDE5 Inhibitor Therapy on Cardiomyocyte Metabolism in Single Ventricle Heart DiseaseDOI 10.1101/2025.03.31.646497
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